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This could be because: you are over 35 you have had a previous pregnancy where the baby had problems such as a chromosome abnormality or another serious health condition you have a family history of a condition such as cystic fibrosis or muscular dystrophy an antenatal screening test, such as the combined first trimester screening test or the non-invasive prenatal test NIPT , has suggested that the baby may have a health problem A CVS is usually done between 11 and 14 weeks of pregnancy.
CVS or amniocentesis? How is it performed? The needle does not enter the amniotic sac or go near the baby. The procedure is performed under local anaesthetic. Transcervical CVS — A tube is inserted through your cervix the neck of the womb and observed by ultrasound.
How does CVS work? You may or may not be asked to have a full bladder right before the procedure. Depending on the position of the uterus and placenta, a full or empty bladder may help move the uterus into a better position for the procedure. A CVS procedure may be done on an outpatient basis, or as part of your stay in a hospital.
An ultrasound will be performed to check the fetal heart rate, and the position of the placenta, fetus, and umbilical cord. Based on the location of the placenta, the CVS procedure will be performed through your cervix transcervical or through your abdominal wall transabdominal.
The doctor will insert an instrument called a speculum into your vagina so that he or she can see your cervix. Cells will be gently suctioned through the tube into a syringe. You may feel a twinge or slight cramping. More than one sample may be needed to obtain enough tissue for testing. For an abdominal CVS, your abdomen will be cleansed with an antiseptic. You will be instructed not to touch the sterile area on your abdomen during the procedure. The doctor may inject a local anesthetic to numb the skin.
If a local anesthetic is used, you will feel a needle stick when the anesthetic is injected. This may cause a brief stinging sensation. Ultrasound will be used to help guide a long, thin, hollow needle through your abdomen and into the uterus and placenta. This may be slightly painful, and you may feel a cramp as the needle enters the uterus. Cells will be gently suctioned into a syringe. The needle will then be removed. An adhesive bandage will be placed over the abdominal needle insertion site.
If you are Rh negative, you may be given Rho D immune globulin. This is a specially developed blood product that can prevent an Rh negative mother's antibodies from reacting to Rh positive fetal cells. Contact a health care provider if you have questions about your health. What is chorionic villus sampling CVS? Other names: CVS test. What is it used for? These include: Down syndrome , a disorder that causes intellectual disabilities, certain physical features, and various health problems.
Cystic fibrosis , a disease that causes mucus buildup in the lungs and other organs, making it hard to breathe. Sickle cell disease , a disorder of the red blood cells. It can cause pain, infections, organ damage, and strokes. Tay-Sachs disease , a disorder that causes fatty proteins to build up in the brain.
It affects sight, hearing, and mental development. Most children with Tay-Sachs die by the age of 5. Why do I need a CVS test?
Risk factors include: Age. Women age 35 and older have a higher risk of having a baby with Down syndrome or another genetic disorder.
Family history of a genetic disorder Having another child with a genetic disorder You may also need CVS testing if you had abnormal results on a prenatal screening test. What happens during a CVS test? The sample is taken through the cervix. The cervix is the lower, narrow end of the uterus that opens into the vagina.
During a transabdominal CVS, your provider will: Clean your abdomen with an antiseptic. Apply a numbing medicine to your abdomen. Insert a long, thin needle through your abdomen and uterus and into the placenta. This can be done through your cervix transcervical or your abdominal wall transabdominal.
You can resume your normal activity level after the procedure. However, you might consider avoiding strenuous exercise and sexual activity for a day. Meanwhile, the tissue sample will be analyzed in a lab. Results might take a few days to a week or so, depending on the complexity of the lab analysis. Your health care provider or a genetic counselor will help you understand your chorionic villus sampling results.
Occasionally, test results are unclear and amniocentesis — another prenatal diagnostic test — is needed to clarify the diagnosis. With chorionic villus sampling, there's a rare chance of a false-positive test — when the test is positive, but no disease exists. It's also important to remember that chorionic villus sampling can't identify all birth defects, including spina bifida and other neural tube defects.
If chorionic villus sampling indicates that your baby has a chromosomal or genetic condition that can't be treated, you might be faced with wrenching decisions — such as whether to continue the pregnancy. Seek support from your health care team and your loved ones during this difficult time. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. This content does not have an English version.
This content does not have an Arabic version. Overview Chorionic villus sampling Open pop-up dialog box Close. Chorionic villus sampling During chorionic villus sampling, a thin tube is guided through the cervix shown above or a needle is inserted into the uterus to remove a sample of chorionic villus cells from the placenta.
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