If needed, they can prescribe antibiotics to treat your infection. Dexilant may cause abdominal pain. In comparison, 3. If you have abdominal pain, it may go away on its own. They can suggest ways to help relieve your symptoms.
Dexilant may cause headaches. Talk with your doctor if you have a headache that lasts several days. As with most drugs, some people can have an allergic reaction after taking Dexilant. Symptoms of a mild allergic reaction can include:.
A more severe allergic reaction is rare but possible. Call your doctor right away if you have a severe allergic reaction to Dexilant. They can prescribe medications to help relieve your symptoms. They may also switch you from Dexilant to a different medication. People taking Dexilant for long periods of time can have bone fractures.
In particular, they may have fractures in their hips, wrist, or spine. But if you take Dexilant for longer than 1 year, or if you take more than one dose per day, you are more likely to have a bone fracture. People using Dexilant long term may also be more likely to develop osteoporosis bone loss. The following information describes dosages that are commonly used or recommended.
However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs. Dexilant comes as capsules containing the drug dexlansoprazole. The usual dosage of Dexilant for erosive esophagitis is 60 mg once daily. Your doctor will prescribe Dexilant for up to 8 weeks. In this case, your doctor will prescribe Dexilant for up to 6 months.
The recommended dosage is a mg capsule of Dexilant each day. The recommended dosages of Dexilant for children ages 12 to 17 years old are the same as for adults. However, the recommended treatment length for children can vary. Below is a list with the suggested treatment lengths for children ages 12 to 17 years old.
If you miss a dose of Dexilant, take the missed dose as soon as possible. Doing so could raise your risk of side effects. How long you should take Dexilant will depend on your age and your condition. In general, your doctor will likely try to avoid having you take Dexilant as a long-term treatment.
Other drugs are available that can treat your condition. Some may be a better fit for you than others. They can tell you about other medications that may work well for you.
Note: Some of the drugs listed here are used off-label to treat these specific conditions. Examples of other drugs that may be used to treat symptoms of gastroesophageal reflux disease GERD include:.
You may wonder how Dexilant compares to other medications that have similar uses. Here we look at how Dexilant and Nexium are alike and different. Dexilant is a prescription medication.
Nexium is available as a prescription medication and an over-the-counter medication. Both Dexilant and Nexium can be used in adults, but their use in children varies. Dexilant is approved for use in children ages 12 to 17 years old. Nexium is approved for use in children ages 1 to 17 years old.
Dexilant contains the drug dexlansoprazole. Nexium contains the drug esomeprazole. Both belong to the same class of drugs, called proton pump inhibitors. This means they work the same way in your body. Dexilant and Nexium have some similar side effects and others that differ. Below are examples of these side effects. These lists contain examples of more common side effects that can occur with Dexilant, with Nexium, or with both drugs when taken individually.
This list contains examples of serious side effects that can occur with Dexilant and Nexium when taken individually. Of that group, 88 people received Dexilant and 87 people received Nexium. In the group of people who took Dexilant, The use of Dexilant and Nexium has also been compared through literature reviews. These reviews analyzed the use of Dexilant and Nexium in people with erosive esophagitis and nonerosive reflux disease, a type of GERD.
In people with erosive esophagitis, Dexilant and Nexium were found to have similar effectiveness. However, Dexilant was found to be more effective than Nexium in treating nonerosive reflux disease.
People with this type of GERD who took Dexilant were more likely to experience relief of heartburn symptoms compared with people who took Nexium. Dexilant and Nexium are brand-name drugs. There is currently no generic form of Dexilant available. Nexium is available in generic form, which is called esomeprazole. Brand-name medications usually cost more than generics. According to estimates on GoodRx.
Omeprazole has uses similar to those of Dexilant. Dexilant is a brand-name prescription medication that contains the drug dexlansoprazole. Dexilant is approved for use in adults and in children ages 12 years and older. Omeprazole is a generic drug that also comes as the brand-name drug Prilosec available as a prescription and over-the-counter drug.
Omeprazole can be used to treat many conditions, including:. Dexilant and omeprazole belong to the same class of drugs, called proton pump inhibitors. Dexilant and omeprazole have some similar side effects and others that differ. These lists contain examples of more common side effects that can occur with Dexilant, with omeprazole, or with both drugs when taken individually.
This list contains examples of serious side effects that can occur with Dexilant and with omeprazole when taken individually. But studies have found both Dexilant and omeprazole to be effective for treating erosive esophagitis and symptoms of GERD.
Dexilant is a brand-name drug. There are currently no generic forms of Dexilant available. Omeprazole is a generic drug. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works.
Other interactions can increase side effects or make them more severe. Below is a list of medications that can interact with Dexilant.
Before taking Dexilant, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Warfarin is an anticoagulant medication blood thinner used in people with blood clots. Taking warfarin with Dexilant can raise the amount of warfarin in your body.
Too much warfarin can raise your risk of excessive bleeding. If uncontrolled, excessive bleeding can lead to death. They can help make sure your warfarin dosage is safe to take with Dexilant. Methotrexate is a common medication used in people with cancer and autoimmune conditions, such as rheumatoid arthritis or psoriasis. Dexilant can increase the amount of methotrexate in your body if you take these drugs together.
Too much methotrexate can be toxic and can cause serious side effects, including severe infections. They may also have you stop taking Dexilant and switch to a different medication. Digoxin is a common medication used in people with heart problems. Dexilant can increase how much digoxin is in your body if you take these drugs together. Too much digoxin can cause serious side effects, including vision problems and confusion.
The use of tacrolimus is very common in people who have undergone organ transplants. Taking tacrolimus with Dexilant can increase the amount of tacrolimus in your body. High amounts of tacrolimus can cause serious side effects, including kidney problems. Rifampin is an antibiotic used to treat bacterial infections. Dexilant may not be effective in people taking rifampin. This is because rifampin decreases the amount of Dexilant in your body if you take these drugs together.
They may ask you to stop taking rifampin and switch to a different antibiotic. Voriconazole is used in people with fungus infections. Taking voriconazole with Dexilant can increase the amounts of Dexilant in your body.
High amounts of Dexilant can cause side effects such as diarrhea and nausea. Taking antiretroviral drugs which treat HIV with Dexilant can affect the amount of antiretroviral drugs in your body. Dexilant lowers the amount of some antiretrovirals in the body and increases the amount of others. Lower amounts of antiretrovirals in the body can make the drugs less effective. Potential Effects on Gastrointestinal Health PPIs not only affect oral medications in a variety of ways, they also alter gut flora by increasing the pH of the stomach, allowing ingested bacteria to survive the usual harsh acid environment.
Clopidogrel and proton pump inhibitors-where do we stand in ? World J Gastroenterol. Elsevier Inc. The comparative effects of single intravenous doses of omeprazole and famotidine on intragastric pH. J Gastroenterol. Early effects of intravenous administrations of lansoprazole and famotidine on intragastric pH.
Managing potential drug-drug interactions between gastric acid-reducing agents and antiretroviral therapy: experience from a large HIV-positive cohort. Diana G, Gregory H. Minor effect of multiple dose omeprazole on the pharmacokinetics of digoxin after a single oral dose. Br J ClinPharmacol. Tetsuhide I, Robert J. Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium.
Curr Gastroenterol Rep. Emmae N, Ramsay, Nicole L, et al. Proton pump inhibitors and the risk of pneumonia: a comparison of cohort and self-controlled case series designs. Published online Jun Proton-pump inhibitors and the risk of antibiotic use and hospitalization for pneumonia.
Again, these articles looked at the medical records of hundreds of thousands of patients and found a small increased risk in patients using PPIs. Additionally, like the hip fracture study, other medical illnesses such as diabetes, heart and lung disease were also important risk factors. The Canadian Task Force for Preventative Health Care recently published recommendations for the prevention of osteoporosis in women.
It mentioned major risk factors such as advanced age, family history of osteoporosis, early menopause, the propensity to fall and minor risk factors such as being thin, smoking, excess alcohol or caffeine intake.
We may learn that long term PPI use will be considered a minor risk factor. If you need to take a PPI, you should talk with your doctor about your risk of osteoporosis. If you have other risk factors, you may need a bone density test. You may simply need to take exercise more or take calcium supplements. You may need to take one of the many excellent medicines for osteoporosis.
It has probably been wishful thinking that the long-term use of PPIs was perfectly safe. Like most medications, there are side-effects and complications. Fortunately the overall risk of long-term PPI use still seems to be relatively small. There any many people taking PPIs that could be using a less powerful medication. However, most people who need to take a PPI should be able to safely continue to take it without the fear of serious complications.
A study of individuals with typical reflux symptoms persisting despite treatment with proton pump inhibitors PPIs , which limit acid secretion in the stomach, aimed to determine the underlying cause of reflux symptoms not responding to PPI therapy. The study found that approximately one-third of the patients suffer from disorders other than gastroesophageal reflux disease GERD , predominantly functional heartburn , concluding that this explains, at least partly, why many patients will not benefit from acid inhibitory treatment.
Source: Herregods TVK, et al. Neurogastroenterol Motil. September IFFGD is a nonprofit education and research organization. Our mission is to inform, assist, and support people affected by gastrointestinal disorders. Our original content is authored specifically for IFFGD readers, in response to your questions and concerns. If you found this article helpful, please consider supporting IFFGD with a small tax-deductible donation. IFFGD is a leader in the fight for more research to improve diagnostic and treatment options for gastrointestinal GI disorders.
With donations from people like. Do I Need Another Endoscopy? Question I underwent an endoscopic exam about 1 year ago and was diagnosed with gastroesophageal reflux disease GERD. This information is in no way intended to replace the guidance of your doctor. All Rights Reserved. About GERD. What is GERD? Dexlansoprazole Dexilant was FDA approved in Dexilant was originally known as Kapidex. Additional Safety Information Source: U. Do not stop taking your proton pump inhibitor unless told to do so by your healthcare professional.
Be aware that an increased risk of fractures of the hip, wrist, and spine has been reported in some studies of patients using proton pump inhibitors. The greatest increased risk for these fractures was seen in patients who receive high doses of these medications or use them longer a year or more. Be aware that the OTC proton pump inhibitors should only be used as directed for 14 days for the treatment of frequent heartburn.
0コメント